PACLITAXEL-INDUCED PERIPHERAL NEUROPATHY IS CAUSED BY
Web Mar 4, 2020 Paclitaxel induces peripheral neuropathy as a side effect of cancer treatment. The underlying causes are unclear, but epidermal, … From nature.com Author Anthony M. Cirrincione, Adriana D. Pellegrini, Jessica R. Dominy, Marisa E. Benjamin, Irina Utkina-S...Publish Year 2020
DISCOVERY RAISES PROSPECT OF NEW NEUROPATHY TREATMENTS
Web Her research showed that degeneration is caused by perturbations in the epidermis due to an increase in matrix-metalloproteinase 13 (MMP-13), … From neuropathyjournal.org Estimated Reading Time 5 mins
Web Jun 24, 2016 Treating the zebrafish with pharmacologic agents that block MMP-13 activity resulted in improved skin defects and reversed the chemotherapy-induced nerve damage. From medscape.com
Web Apr 15, 2016 Her research showed that degeneration is caused by perturbations in the epidermis due to an increase in matrix-metalloproteinase 13 (MMP-13), an enzyme that degrades the collagen, … From technologynetworks.com
SELECTIVE MMP-13 INHIBITORS: PROMISING AGENTS FOR THE …
Web Matrix metalloproteinase-13 (MMP-13), an important member of matrix metalloproteinases (MMPs) family, plays a vital role by degrading type II collagen in articular cartilage and … From pubmed.ncbi.nlm.nih.gov Author Yichao Wan, Wei Li, Zhipeng Liao, Mi Yan, Xuwang Chen, Zilong TangPublish Year 2020
MMP-13 ENZYME AND PH RESPONSIVE THERANOSTIC NANOPLATFORM FOR ...
Web Aug 27, 2020 11 Research Centre for Regenerative Medicine, Department of Orthopedics, The First Affiliated Hospital of Gaungxi Medical University, Nanning, 530021, China. … From pubmed.ncbi.nlm.nih.gov
NEW INSIGHTS ON THE MMP-13 REGULATORY NETWORK IN THE …
Web Nov 10, 2017 first compared the DNA methylation status of four degradative enzymes (i.e., MMP-3, MMP-9, MMP-13, and ADAMTS-4) between OA and non-OA samples. Of the … From arthritis-research.biomedcentral.com
MMP-13 ENZYME AND PH RESPONSIVE THERANOSTIC NANOPLATFORM FOR ...
Web Aug 27, 2020 The acid environment and overexpressed matrix metalloproteinases-13 (MMP-13) are typical markers in osteoarthritis (OA), which enables the development of … From jnanobiotechnology.biomedcentral.com
MMP13 IS A CRITICAL TARGET GENE DURING THE PROGRESSION OF ...
Web Jan 8, 2013 Matrix metalloproteinase (MMP) 13 is a major enzyme that targets cartilage for degradation. Compared to other MMPs, the expression of MMP13 is more restricted … From arthritis-research.biomedcentral.com
MMP13 IS A CRITICAL TARGET GENE DURING THE PROGRESSION OF ...
Web Jan 8, 2013 The ability of CL82198 to inhibit MMP13 activity in vitro was confirmed by ELISA. Results: The OA progression was decelerated in Mmp13Col2ER mice 8, 12, and … From pubmed.ncbi.nlm.nih.gov
OVERVIEW OF MMP-13 AS A PROMISING TARGET FOR THE TREATMENT OF ...
Web Feb 9, 2021 Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. Matrix … From ncbi.nlm.nih.gov
MMP 13 ENZYME HUMAN RECOMBINANT | COLLAGENASE 3 | PROSPEC
Web Description MMP-13 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (104-471 a.a.) and having a molecular mass of 44.7 kDa. … From prospecbio.com
MMP-13 INHIBITORY ACTIVITY OF THIRTEEN SELECTED PLANT SPECIES FROM …
Web ABSTRACT The methanol extracts of thirteen medicinal plants from Okinawa, Japan were examined for Matrix Metalloproteinase-13 (MMP-13) inhibitory activity. Among the … From scialert.net
Web Apr 14, 2016 Her research showed that degeneration is caused by perturbations in the epidermis due to an increase in matrix-metalloproteinase 13 (MMP-13), an enzyme that … From sciencedaily.com
Web Glucose-induced sensory axon degeneration was prevented upon pharmacological inhibition of ROS with the antioxidant, N-acetylcysteine, and upon pharmacological MMP-13 … From ncbi.nlm.nih.gov
PERIPHERAL NEUROPATHY - SYMPTOMS AND CAUSES - MAYO …
Web Aug 11, 2022 Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms; Sharp, jabbing, throbbing or burning … From mayoclinic.org
OVERVIEW OF MMP-13 AS A PROMISING TARGET FOR THE TREATMENT OF
Web Jan 8, 2021 Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. Matrix … From mdpi.com
Web Apr 15, 2016 The increase in MMP-13 activity could be triggered by oxidative stress, which is also a hallmark of diabetic peripheral neuropathy. In the research, Rieger treated the … From sciencebeta.com
INHIBITION OF MMP-13 PREVENTS DIET-INDUCED OBESITY IN MICE AND
Web MMP-13 is an important protein that is highly expressed in adipose tissue but whose potential role in adipose tissue expansion is poorly characterized. We investigated the … From pubmed.ncbi.nlm.nih.gov
Web Tools Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. [5] [6] It is a member of the matrix metalloproteinase (MMP) family. Like most MMPs, it is … From en.wikipedia.org
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