A COMPREHENSIVE PATHWAY MAP OF IL-18-MEDIATED SIGNALLING
Dec 20, 2019 Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines and was initially described as an IFN-γ-inducing factor derived from anti-CD3-stimulated T-helper (Th)1 cells. IL … From link.springer.com
INTERLEUKINS, FROM 1 TO 37, AND INTERFERON-γ: RECEPTORS, FUNCTIONS, …
Aug 19, 2010 IL-1 plays an important role of the innate immune system, which regulates functions of the adaptive immune system. IL-1α and β are both potent proinflammatory … From jacionline.org
A PROTECTIVE ROLE FOR INTERLEUKIN 18 IN INTERFERON γ-MEDIATED INNATE ...
A protective role for interleukin 18 in interferon γ-mediated innate immunity to Cryptosporidium parvum that is independent of natural killer cells(Q39361853) From wikidata.org
POTENTIAL ROLE FOR INTERLEUKIN-18 IN INHIBITION OF THE DEVELOPMENT OF ...
Jul 12, 2006 The development of a Th1 immune response has been shown previously to be critical in the control of C. parvum infection [3, 4]. We have suggested previously that … From academic.oup.com
IL-18BP MEDIATES THE BALANCE BETWEEN PROTECTIVE AND
Mar 28, 2023 Summary Interleukin-18 (IL-18) promotes natural killer (NK) and T cell production of interferon (IFN)-γ, a key factor in resistance to Toxoplasma gondii, but previous work has … From sciencedirect.com
INTERLEUKIN-18 IS AN ESSENTIAL ELEMENT IN HOST RESISTANCE TO ...
Jan 1, 2004 ABSTRACT Previous studies demonstrated that interleukin-12 (IL-12)-dependent gamma interferon (IFN-γ) responses have a major role in restricting in vivo bacterial growth … From journals.asm.org
PROTECTIVE ROLE OF IL-18 IN HOST DEFENSES AGAINST GROUP B
Jul 4, 2021 Here, we show that IL-18 plays a protective role in host defenses against GBS infection in both adult and neonatal mice by virtue of its ability to induce a protective IFN-γ … From link.springer.com
INTERFERON-GAMMA (IFN-γ): EXPLORING ITS IMPLICATIONS IN INFECTIOUS …
A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous protective functions to heighten immune responses in infections and cancers. It can exhibit its … From degruyterbrill.com
Jun 15, 2003 However, the role of IFN-γ in murine defense against gram-negative infection is inconsistent. Mice deficient in IFN-γ are not resistant to lethal endotoxemia but are resistant … From academic.oup.com
THE ROLE OF IL-18 IN INNATE IMMUNITY - SCIENCEDIRECT
Feb 1, 2000 It has become apparent that IL-18 plays an essential role in NK cell activity and Th1 cell differentiation, as demonstrated by the IL-18 knockout experiment. The Th1 to Th2 … From sciencedirect.com
A PROTECTIVE ROLE FOR INTERLEUKIN 18 IN INTERFERON -MEDIATED INNATE ...
Innate immunity against some intracellular parasitic protozoa involves IL-18-mediated IFN-γ production by NK cells but the role of IL-18 in innate resistance to Cryptosporidium is unknown. From academia.edu
ROLE OF IL-18 IN INFLAMMATORY DISEASES | SPRINGERLINK
Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G (2004) Interferon regulatory factor-1 as a protective gene in intestinal inflammation: Role of TCR gamma delta T … From link.springer.com
A J O R A R T I C L E Protective Role for Interleukin 18 in Interferon γ–Mediated Innate Immunity to Cryptosporidium parvum That Is Independent of Natural Killer Cells From researchgate.net
INTERFERON-γ PRODUCTION AND HOST PROTECTIVE RESPONSE AGAINST ...
Apr 1, 2004 Interferon (IFN)-γ plays an essential role in host defense against infection with Mycobacterium tuberculosis, and its synthesis is critically regulated by interleukin (IL)-12, IL-18 … From sciencedirect.com
ROLES FOR NK CELLS AND AN NK CELL-INDEPENDENT SOURCE OF INTESTINAL ...
Aug 17, 2009 A gamma interferon (IFN-gamma)-dependent innate immune response operates against the intestinal parasite Cryptosporidium parvum in T- and B-cell-deficient SCID mice. … From europepmc.org
PROATHEROGENIC ROLE OF INTERLEUKIN-18: EFFECTS ON INFLAMMATION AND ...
Aug 25, 2012 Conclusion We currently view IL-18 as a cytokine with proinflammatory activity operating through innate as well as adaptive pathways of immunity. Work by us and others … From academic.oup.com
A PROTECTIVE ROLE FOR INTERLEUKIN 18 IN INTERFERON γ-MEDIATED INNATE ...
Innate immunity against some intracellular parasitic protozoa involves interleukin 18 (IL-18)—mediated interferon γ (IFN-γ) production by natural killer (NK) cells, but the role of IL-18 … From onesearch.library.rice.edu
Oct 1, 2004 Its ability to potently enhance the production of interferon-γ indicates in particular the crucial function of interleukin-18 as an immunomodulatory molecule. In fact, high levels of … From sciencedirect.com
PROTECTIVE ROLE FOR INTERLEUKIN 18 IN INTERFERON γ–MEDIATED INNATE ...
Apr 19, 2012 Abstract Innate immunity against some intracellular parasitic protozoa involves interleukin 18 (IL-18)–mediated interferon γ (IFN-γ) production by natural killer (NK) cells, but … From academic.oup.com
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